The advent of bisphosphonate was once a medical breakthrough which would benefit millions who are suffering or at risk of suffering from osteoporosis. Unfortunately, the recent past was not a good era for these drugs as more complaints against them arise; in fact a bisphosphonate review was published in a preliminary event to FDA (the Food and Drug Administration) Advisory meeting. Thinking that these patients, who might have developed osteoporosis as a complication of another disease, resorted to these drugs with the hopes of getting treat ended up with a whole new problem is so depressing.
it's not a wonder why many people succumb into this bone-debilitating illness. Aside from the risk factors that would involve a wide population, a number of disease would actually lead to the development of this brittle bone disease. If you are suffering from any of these diseases then you might need to look out for the health of your bones.
Autoimmune disorders like Rheumatoid Arthritis (RA) and Lupus
Autoimmune diseases arise from an overactive immune response to a substance that is not foreign to the body. Treatment of RA and Lupus often include the use of steroids which may be taken on a long-term basis. Steroids may cause a gradual decrease in bone loss (although RA itself may also cause bone loss) thus increasing the likelihood of osteoporosis.
Digestive and Gastrointestinal disorders
Diseases like celiac disease and inflammatory bowel diseases (IBD) namely Crohn's disease and ulcerative colitis can cause bone loss. This is mainly due to inability of the body to properly absorb nutrients like vitamin D and calcium. The same goes with those who underwent gastric bypass procedures which alter the structure of the digestive system.
Endocrine/Hormonal Disorders
Diabetes, especially type 1, has been known to cause bone loss; hence, putting its patients at risk of osteoporosis. Diseases such as hyperparathyroidism and hyperthyroidism may also cause rapid bone loss and fragile bones. Low levels of sex hormones, namely estrogen and testosterone, may result in poor bone health.
There are still many diseases that can cause osteoporosis. People in this situation should not have to deal with more problems like the adverse effects of bone medications like Fosamax [http://www.fosamaxfemurfracturelawsuit.com/updates/bisphosphonate-review-published-in-run-up-to-fda-advisory-meeting/]. In the news are people contending for a Fosamax lawsuit because of the alleged harmful effects of the drug but we know for sure that these people never wanted to dwell on those problems in the first place.
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