Toledo's position to the south of Madrid suggests it would make a perfect stop-off point on the way from Madrid to Seville. Unfortunately, there are no direct trains or buses from Toledo to Seville, so most people think they have to hire a car. You have two options for getting from Toledo to Seville by public transport:

• Via Madrid
• Via Ciudad Real

See also:

• Toledo to Granada without having to go via Madrid

• Toledo Travel Guide
• 50 Things to Do in Seville

Toledo to Seville via Madrid

Frustrating as it may be to travel north before you can go south, the quickest and simplest way of traveling from Toledo to Seville is to go back to Madrid and take the high-speed AVE train from Madrid to Seville. The two trains depart from the same train station, so there is no need to transfer. Read more about the AVE train in Spain.
For those on a tighter budget, once back in Madrid you can take a bus from Madrid to Seville, which is a lot cheaper than the train but take a lot longer and requires a transfer. Read more about Madrid train and bus stations.

Toledo to Seville via Ciudad Real

Traveling from Toledo to Seville via Ciudad Real is the most direct way of traveling between the two cities but it requires using both bus and train. Furthermore, there is little to do in Ciudad Real, so you'll just be using the city as a transfer point.
From Toledo to Ciudad Real, you'll have to take a bus. The bus is run by Aisa Grupo.

There is a bus at 7.15am (arriving at 8.45am) or 9.30am (arriving at 11.25am) and it costs around 10 euros. After that, you'll need to take the high-speed train from Ciudad Real to Seville, which requires traveling across Ciudad Real from the bus station to the train station. There are trains at 9.51am, 12.13pm and 1.51pm. The journey takes under one-and-three-quarter hours and costs about 65€.

This journey takes just over three hours of travel, plus transfer time, and costs around 75€.